How often should I clean my Savage Model muzzle loader? Savage Moderator April 11, 2013 18:58 Updated Follow When using smokeless powder – Every 50-60 shots or every other range session. When using Pyrodex® or black powder – Not more than 20 shots and same day after each use Related articles How often should I change the vent liner? How should I premeasure my powder for my muzzle loader MLII? Can I shoot the 5.56x45 NATO ammunition in my 223 Rem? 7.62 X 51 in 308 WIN? How do I clean and care for my centerfire/bolt-action firearm? How do I clean the muzzlebrake?